Connective tissue implants to augment damaged tissue with functional tissue.
TECHNOLOGY
Connective tissue contains functional ECM components that support constructive remodeling1 .
CTM develops and creates immune-privileged Connective Tissue and ExtraCellular Matrix (ECM) structural implants. Our products are designed to cover or protect tissues intra-operatively and to augment or replace damaged or inadequate tissue at the surgical site.
The ECM is a combination of both structural and functional components including collagens, glycoproteins, proteoglycans, mucins, elastic fibers, and growth factors2 that form a three-dimensional matrix, providing structural support to the body’s tissues and cells.3
Constructive remodeling is the body's process of forming site-appropriate, functional tissue.1
Injuries can lead to significant tissue damage, and even after surgical repair these sites often lack adequate functional tissue to remodel successfuly. This can result in post-operative complications, failure, or re-injury. In order to augment the tissue damage, surgeons look to the most native tissue options to increase the likelihood of successful repair.
Connective tissue is the most prolific tissue type, and is ubiquitous throughout the body. This allows us to create an ideal ECM implant option to augment tissue damage and support constructive remodeling in a diverse range of surgical sites.
A SURGICAL SOLUTION
CTM helps physicians deal with issues that are beyond their control.
01
Augment damaged tissue with functional tissue
02
Provide structural support at the surgical site
03
Support the body's constructive remodeling process
PRODUCTS
Ideal options designed for any surgical approach.
Inject
Pack, Fill, Spread
Wrap, Cover, Protect
STORAGE & HANDLING
5 year shelf life
Store at ambient temperature
Sterilized by irradiation
Single patient, one-time use only
Only for use by a registered physician
INTENDED USE
CTM implants are intended for homologous use to cover or protect4, or to supplement or replace damaged or inadequate connective tissue.5
CONTACT US FOR MORE INFORMATION
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References: (1.) Brown, BN, Badylak, SF. Extracellular matrix as an inductive scaffold for functional tissue reconstruction. Transl Res. 2014 April ; 163(4): 268–285. doi:10.1016/j.trsl.2013.11.003. (2.) Hynes RO, Naba A. Overview of the matrisome–an inventory of extracellular matrix constituents and functions. Cold Spring Harbor Perspect Biol. 2012; 4:a004903. (3.) Badylak, SF, Freytes, DO, Gilber, TW. Extracellular matrix as a biological scaffold material: Structure and function. Acta Biomater. 5 (2009) 1–13. (4.) Reference on file with CTM Biomedical. (5.) Reference on file with CTM Biomedical.
